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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saavedra, Alex | RP | Chicago Eclipse | 18 | 11/05/2044 | Carolina | PUR | Left | Left | 6' 4" | 185 lbs | - |
| Saavedra, David | CF | Jacksonville Pilots | 17 | 04/04/2045 | San Juan | PUR | Right | Right | 6' 4" | 205 lbs | - |
| Saavedra, Jorge | 3B | Cairo Pharaohs | 18 | 03/07/2044 | San Cristóbal | DOM | Right | Right | 6' 5" | 200 lbs | - |
| Saavedra, Tony | CF | Manhattan Slice | 19 | 05/01/2043 | Havana | CUB | Left | Right | 6' 6" | 195 lbs | - |
| Saavedra, Vinny | SP | Free Agent | 17 | 05/16/2045 | Camagüey | CUB | Left | Left | 5' 9" | 155 lbs | - |
| Sabater, John | SP | Free Agent | 17 | 03/31/2045 | Villa Isabela | DOM | Right | Right | 6' 6" | 195 lbs | - |
| Sabato, Bernard | RP | Milwaukee Millers | 25 | 05/23/2037 | Terni | ITA | Switch | Right | 6' 0" | 190 lbs | $600,000 |
| Sabio, Juan | SP | Vancouver Pioneers | 17 | 09/15/2045 | Condado | CUB | Right | Right | 6' 2" | 180 lbs | - |
| Sacadura, Tome | SP | Houghton Gremlins | 18 | 02/05/2045 | Tucupita | VEN | Left | Left | 6' 3" | 180 lbs | - |
| Saenz, Agustin | 3B | Free Agent | 21 | 06/18/2041 | León | MEX | Right | Right | 6' 3" | 195 lbs | - |
| Saenz, Alex | SS | Free Agent | 18 | 10/27/2044 | Puebla | MEX | Right | Right | 6' 2" | 190 lbs | - |
| Saenz, Dave | 3B | Free Agent | 23 | 01/31/2040 | San Juan | PUR | Right | Right | 6' 4" | 200 lbs | - |
| Saenz, Manuel | SP | Buffalo Bison | 19 | 03/27/2043 | Santo Domingo | DOM | Left | Left | 6' 6" | 195 lbs | - |
| Saenz, Ruben | SP | Buffalo Bison | 18 | 07/02/2044 | Santa Clara | CUB | Left | Right | 6' 2" | 180 lbs | - |
| Saenz, Victor | SP | Maple Marauders | 16 | 02/09/2046 | Sagua la Grande | CUB | Right | Right | 6' 1" | 170 lbs | - |
| Saenz, Victor | 2B | Eureka Hornets | 19 | 11/24/2043 | San Juan | PUR | Right | Right | 5' 10" | 175 lbs | - |
| Saez, Danny | SP | Montreal Mounties | 18 | 01/15/2045 | Bayamón | PUR | Right | Right | 6' 2" | 175 lbs | - |
| Sagace, Dante | RP | Seattle Sasquatch | 17 | 05/30/2045 | Santa Clara | CUB | Right | Right | 6' 1" | 170 lbs | - |
| Sahagun, Marco | SP | Cabo San Lucas Toreros | 16 | 04/14/2046 | Saucillo | MEX | Right | Right | 6' 3" | 180 lbs | - |
| Sai, Hisatomo | SP | Walnut Creek Warriors | 18 | 09/20/2044 | Utsunomiya | JPN | Right | Left | 6' 2" | 190 lbs | - |
| Sai, Toji | SP | Buffalo Bison | 17 | 11/11/2045 | Hikone | JPN | Right | Right | 6' 3" | 185 lbs | - |
| Saito, Shoji | SP | Asheville Moonshiners | 17 | 11/22/2045 | Tokyo | JPN | Right | Right | 6' 5" | 195 lbs | - |
| Saito, Sumiki | SP | Asheville Moonshiners | 16 | 06/14/2046 | Kochi | JPN | Left | Right | 6' 0" | 170 lbs | - |
| Saito, Takamori | SS | Buffalo Bison | 20 | 12/21/2042 | Naha | JPN | Right | Right | 6' 2" | 185 lbs | - |
| Saito, Yoshinari | RF | Vancouver Pioneers | 16 | 08/06/2046 | Sayama | JPN | Right | Right | 6' 5" | 200 lbs | - |
| Sakai, Kenji | SP | El Paso Mavericks | 17 | 06/19/2045 | Kashiwa | JPN | Right | Right | 6' 4" | 190 lbs | - |
| Sakamoto, Kenichi | RF | Jacksonville Pilots | 19 | 09/10/2043 | Chiba | JPN | Left | Left | 6' 2" | 205 lbs | - |
| Sakamoto, Mokuo | SP | Bighorn Bison | 19 | 01/28/2044 | Tokai | JPN | Right | Right | 6' 2" | 185 lbs | - |
| Sakamoto, Natsuo | RP | Free Agent | 17 | 05/15/2045 | Kani | JPN | Right | Right | 6' 1" | 175 lbs | - |
| Sakamoto, Nobuhiro | C | Jacksonville Pilots | 16 | 03/19/2046 | Sendai | JPN | Right | Right | 6' 7" | 220 lbs | - |
| Sakamoto, Unpei | LF | El Paso Mavericks | 17 | 12/30/2045 | Honjo | JPN | Right | Left | 6' 2" | 170 lbs | - |
| Sakuma, Mitsuyoshi | 1B | Free Agent | 17 | 07/11/2045 | Kawasaki | JPN | Left | Left | 6' 4" | 210 lbs | - |
| Salas, Carlos | SS | Montreal Mounties | 17 | 05/03/2045 | Sabana Grande | PUR | Right | Right | 6' 0" | 160 lbs | - |
| Salas, Pedro | SP | Bighorn Bison | 19 | 12/08/2043 | Jagüey Grande | CUB | Right | Right | 5' 9" | 170 lbs | - |
| Salas, Roger | RP | Dallas Texans | 18 | 04/02/2044 | San Pedro de Macorís | DOM | Left | Left | 6' 6" | 200 lbs | - |
| Salazar, Alberto | SP | Walnut Creek Warriors | 19 | 08/30/2043 | Tijuana | MEX | Right | Right | 5' 11" | 170 lbs | - |
| Salazar, Angelo | SP | Jacksonville Pilots | 16 | 02/03/2047 | Corozal | PUR | Right | Right | 6' 2" | 180 lbs | - |
| Salazar, Antonio | SP | Asheville Moonshiners | 17 | 07/12/2045 | Ponce | PUR | Switch | Right | 6' 1" | 175 lbs | - |
| Salazar, Antonio | 2B | Cabo San Lucas Toreros | 18 | 03/15/2044 | Guantanamo | CUB | Right | Right | 6' 0" | 180 lbs | - |
| Salazar, Antonio | C | Houghton Gremlins | 19 | 01/30/2044 | San Juan | PUR | Right | Right | 6' 4" | 200 lbs | - |
| Salazar, Armando | LF | Vancouver Pioneers | 18 | 10/01/2044 | San Juan | PUR | Right | Right | 6' 1" | 200 lbs | - |
| Salazar, Chris | RF | Kansas City Tornadoes | 17 | 06/24/2045 | Santa Clara | CUB | Right | Right | 6' 1" | 180 lbs | - |
| Salazar, Danny | 3B | Pennsylvania Butterflies | 17 | 05/31/2045 | Santo Domingo | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Salazar, Danny | SP | Free Agent | 17 | 06/05/2045 | Mexico City | MEX | Right | Right | 6' 2" | 170 lbs | - |
| Salazar, David | SS | Free Agent | 22 | 11/25/2040 | Salina Cruz | MEX | Right | Right | 6' 4" | 200 lbs | - |
| Salazar, Ed | SS | Asheville Moonshiners | 18 | 04/09/2044 | Madera | MEX | Left | Right | 6' 2" | 200 lbs | - |
| Salazar, Emilio | SP | Free Agent | 34 | 03/24/2028 | Havana | CUB | Right | Right | 6' 7" | 195 lbs | - |
| Salazar, Felix | C | Free Agent | 20 | 06/24/2042 | Santo Domingo | DOM | Right | Right | 6' 2" | 200 lbs | - |
| Salazar, Jose | SP | Jacksonville Pilots | 19 | 02/22/2043 | San Juan | PUR | Right | Right | 6' 1" | 170 lbs | - |
| Salazar, Jose | LF | Free Agent | 21 | 07/23/2041 | Santiago | DOM | Right | Right | 6' 6" | 200 lbs | - |
| Salazar, Juan | SP | Quebec Armada | 18 | 05/20/2044 | Ecatepec | MEX | Switch | Right | 6' 2" | 175 lbs | - |
| Salazar, Luis | SP | Kansas City Tornadoes | 17 | 09/17/2045 | Higüey | DOM | Right | Right | 6' 7" | 200 lbs | - |
| Salazar, Luis | SP | Vancouver Pioneers | 18 | 08/15/2044 | Santiago de Cuba | CUB | Switch | Right | 5' 11" | 165 lbs | - |
| Salazar, Melvin | C | Eureka Hornets | 17 | 11/23/2045 | Bonao | DOM | Left | Left | 6' 5" | 200 lbs | - |
| Salazar, Mike | SP | Free Agent | 19 | 08/15/2043 | Hato Mayor | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Salazar, Nestor | SP | Bloomington Blazers | 16 | 05/06/2046 | San Francisco de Macorís | DOM | Left | Left | 6' 2" | 180 lbs | - |
| Salazar, Oscar | CF | Free Agent | 16 | 09/04/2046 | Guadalajara | MEX | Left | Left | 5' 10" | 160 lbs | - |
| Salazar, Oscar | C | Free Agent | 31 | 02/11/2031 | Baní | DOM | Right | Right | 6' 1" | 200 lbs | - |
| Salazar, Roberto | 3B | Pennsylvania Butterflies | 17 | 06/04/2045 | Santo Domingo | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Salazar, Willie | RP | Buffalo Bison | 17 | 02/28/2045 | Hidalgo | MEX | Right | Right | 6' 4" | 185 lbs | - |
| Salazaro, Tony | SP | Montreal Mounties | 17 | 07/06/2045 | La Vega | DOM | Left | Left | 6' 7" | 200 lbs | - |
| Salcedo, Angelo | SP | Eureka Hornets | 17 | 11/25/2045 | Sabana Grande de Boya | DOM | Right | Right | 5' 9" | 150 lbs | - |
| Salcedo, Felipe | SP | Free Agent | 17 | 06/25/2045 | Barranquilla | COL | Right | Right | 6' 4" | 185 lbs | - |
| Salcedo, Jesus | SP | San Francisco Earthquakes | 16 | 07/17/2046 | Santo Domingo | CUB | Left | Left | 5' 11" | 165 lbs | - |
| Salcedo, Manny | SP | Cairo Pharaohs | 17 | 10/25/2045 | Güines | CUB | Right | Right | 6' 4" | 190 lbs | - |
| Salcido, Alex | SP | Cairo Pharaohs | 19 | 04/09/2043 | Camagüey | CUB | Left | Left | 6' 0" | 165 lbs | - |
| Salcido, Marcos | 3B | Free Agent | 17 | 12/22/2045 | Tlalnepantla | MEX | Right | Right | 6' 1" | 200 lbs | - |
| Saldana, Armando | 2B | Manhattan Slice | 19 | 04/30/2043 | San Juan | PUR | Right | Right | 6' 5" | 205 lbs | - |
| Saldana, Danny | SP | Pennsylvania Butterflies | 17 | 02/13/2045 | San Juan | PUR | Right | Right | 6' 3" | 180 lbs | - |
| Saldana, Luis | 3B | Chicago Eclipse | 16 | 09/09/2046 | Mao | DOM | Left | Right | 6' 2" | 200 lbs | - |
| Saldana, Luis | SP | Jacksonville Pilots | 18 | 11/07/2044 | Santo Domingo | DOM | Right | Right | 6' 3" | 185 lbs | - |
| Saldana, Melvin | SP | Hawaii Honu | 17 | 10/13/2045 | Ponce | PUR | Right | Right | 6' 2" | 180 lbs | - |
| Saldana, Pedro | RP | Free Agent | 20 | 11/25/2042 | Santo Domingo | DOM | Right | Left | 6' 1" | 185 lbs | - |
| Saldierna, Danny | SP | Montreal Mounties | 19 | 10/21/2043 | Torreón | MEX | Right | Right | 5' 10" | 155 lbs | - |
| Saldivar, Fernando | SP | Chicago Eclipse | 17 | 10/01/2045 | San Sebastian | PUR | Left | Right | 6' 4" | 190 lbs | - |
| Saldivar, Luis | RP | Seattle Sasquatch | 17 | 07/03/2045 | San Juan | PUR | Left | Left | 5' 11" | 165 lbs | - |
| Saldivar, Marco | SP | Buffalo Bison | 19 | 09/08/2043 | San José del Progreso | MEX | Switch | Right | 6' 2" | 180 lbs | - |
| Salgado, Angelo | CF | Bloomington Blazers | 16 | 01/05/2047 | Santo Domingo | DOM | Right | Right | 6' 3" | 180 lbs | - |
| Salgado, Freddy | LF | Seattle Sasquatch | 26 | 12/28/2036 | General Escobedo | MEX | Left | Left | 6' 1" | 195 lbs | $1,200,000 |
| Salgado, Roberto | RF | Free Agent | 33 | 03/05/2029 | San Cristóbal | DOM | Right | Right | 6' 1" | 200 lbs | - |
| Salgado, Victor | 3B | Manhattan Slice | 19 | 03/08/2043 | Córdoba | MEX | Left | Right | 6' 0" | 190 lbs | - |
| Salguero, David | SP | Cabo San Lucas Toreros | 17 | 11/29/2045 | Mexico City | MEX | Right | Right | 5' 11" | 165 lbs | - |
| Salguero, Jesus | 2B | Free Agent | 19 | 02/03/2044 | Guantanamo | CUB | Right | Right | 6' 1" | 200 lbs | - |
| Salinas, Alejandro | SP | Bloomington Blazers | 19 | 09/12/2043 | Guayama | PUR | Switch | Left | 6' 3" | 185 lbs | - |
| Salinas, Alex | SP | Free Agent | 18 | 11/29/2044 | Güines | CUB | Right | Right | 6' 5" | 195 lbs | - |
| Salinas, Bobby | SP | Walnut Creek Warriors | 18 | 03/17/2044 | Aguadilla | PUR | Right | Right | 6' 9" | 200 lbs | - |
| Salinas, Franklin | 2B | Havana Stogies | 18 | 10/08/2044 | Manatí | PUR | Right | Right | 6' 2" | 195 lbs | - |
| Salinas, Jesus | RP | El Paso Mavericks | 17 | 12/20/2045 | Guaynabo | PUR | Switch | Left | 6' 3" | 185 lbs | - |
| Salinas, Juan | SP | Maple Marauders | 16 | 02/23/2046 | Tepatitlan | MEX | Left | Left | 5' 10" | 155 lbs | - |
| Salinas, Oscar | C | Houghton Gremlins | 18 | 02/08/2044 | San Cristóbal | DOM | Right | Right | 6' 5" | 205 lbs | - |
| Salinas, Ruben | 2B | Mexico City Luchadores | 19 | 04/28/2043 | Barcelona | VEN | Right | Right | 6' 2" | 170 lbs | - |
| Salinas, Sergio | SP | Free Agent | 17 | 11/25/2045 | La Vega | DOM | Left | Left | 6' 3" | 180 lbs | - |
| Salinas, Vic | SP | Free Agent | 19 | 03/21/2043 | Bayamo | CUB | Right | Right | 6' 3" | 185 lbs | - |
| Salinas, Victor | SS | Kansas City Tornadoes | 17 | 12/05/2045 | Bayamón | PUR | Right | Right | 6' 2" | 200 lbs | - |
| Salinas, Victor | SS | Manhattan Slice | 17 | 07/01/2045 | Tlalnepantla | MEX | Switch | Right | 6' 1" | 180 lbs | - |
| Salinas, Victor | C | San Francisco Earthquakes | 20 | 01/29/2043 | El Hatillo | VEN | Right | Right | 6' 1" | 195 lbs | - |
| Salstrom, Dusty | 3B | San Francisco Earthquakes | 22 | 03/14/2040 | Bristol | USA | Right | Right | 6' 2" | 170 lbs | $600,000 |
| Salto, Israel | SP | Jacksonville Pilots | 16 | 02/11/2046 | Colombia | CUB | Left | Right | 6' 1" | 170 lbs | - |
| Salvador, Jordan | SP | Cabo San Lucas Toreros | 19 | 10/17/2043 | San Sebastian | PUR | Left | Left | 6' 2" | 185 lbs | - |
| Samaniego, Jon | LF | Seattle Sasquatch | 19 | 12/16/2043 | Río Grande | PUR | Switch | Right | 6' 2" | 200 lbs | - |
| Sambrano, Alex | SP | Bighorn Bison | 19 | 11/17/2043 | Santo Domingo | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Sambrano, Alfredo | RF | Hawaii Honu | 17 | 08/19/2045 | Guacara | VEN | Left | Left | 6' 6" | 210 lbs | - |
| Samuels, Mike | LF | Cairo Pharaohs | 26 | 08/27/2036 | Ridgefield Park | USA | Right | Right | 6' 4" | 200 lbs | $600,000 |
| San Miguel, Melvin | RF | Hawaii Honu | 17 | 03/27/2045 | Santo Domingo | DOM | Right | Left | 6' 2" | 175 lbs | - |
| San Miguel, Raul | SP | Pennsylvania Butterflies | 17 | 04/17/2045 | Florida | CUB | Switch | Right | 6' 3" | 185 lbs | - |
| San Roman, Jorge | SP | Cabo San Lucas Toreros | 19 | 01/05/2044 | Carolina | PUR | Switch | Right | 6' 8" | 200 lbs | - |
| Sanabria, Angel | 1B | Manhattan Slice | 21 | 09/02/2041 | Bayamón | PUR | Right | Right | 6' 1" | 200 lbs | - |
| Sanabria, Luis | SP | Montreal Jazz | 18 | 12/31/2044 | Havana | CUB | Left | Left | 6' 8" | 205 lbs | - |
| Sanabria, Omar | SP | Pennsylvania Butterflies | 19 | 03/06/2043 | Salamanca | MEX | Left | Left | 6' 6" | 195 lbs | - |
| Sancen, Alex | SP | Eagle Rock Ridge Runners | 19 | 09/20/2043 | Pedro Brand | DOM | Right | Right | 6' 4" | 185 lbs | - |
| Sancen, Orlando | 3B | Milwaukee Millers | 19 | 10/08/2043 | Santiago | DOM | Right | Right | 6' 2" | 195 lbs | - |
| Sanches, Ricky | SP | Pennsylvania Butterflies | 16 | 07/24/2046 | Las Guacamayas | MEX | Right | Right | 6' 4" | 185 lbs | - |
| Sanchez, Alejandro | RF | Free Agent | 16 | 10/07/2046 | Jesús María Garza | MEX | Left | Left | 6' 4" | 195 lbs | - |
| Sanchez, Alex | LF | Vancouver Pioneers | 17 | 07/31/2045 | Santo Domingo | DOM | Right | Right | 6' 1" | 195 lbs | - |
| Sanchez, Alex | SP | Manhattan Slice | 18 | 09/20/2044 | Azua | DOM | Right | Left | 6' 3" | 180 lbs | - |
| Sanchez, Alex | CF | Dallas Texans | 18 | 07/11/2044 | Guayama | PUR | Left | Left | 6' 2" | 175 lbs | - |
| Sanchez, Alex | C | San Francisco Earthquakes | 22 | 02/16/2040 | Villa Nueva | GUA | Right | Right | 6' 0" | 200 lbs | $600,000 |
| Sanchez, Angel | C | Jacksonville Pilots | 18 | 09/22/2044 | Caracas | VEN | Left | Right | 6' 4" | 210 lbs | - |
| Sanchez, Angel | LF | Free Agent | 30 | 12/01/2032 | Matagalpa | NCA | Left | Left | 6' 1" | 200 lbs | - |
| Sanchez, Angelo | 2B | Pennsylvania Butterflies | 18 | 12/31/2044 | Santo Domingo | DOM | Right | Right | 6' 0" | 180 lbs | - |
| Sanchez, Angelo | 3B | Mexico City Luchadores | 19 | 12/25/2043 | Victor Rosales | MEX | Right | Right | 5' 10" | 195 lbs | - |
| Sanchez, Antonio | SP | Milwaukee Millers | 16 | 05/26/2046 | Juarez | MEX | Right | Right | 6' 0" | 165 lbs | - |
| Sanchez, Antonio | SS | Free Agent | 17 | 06/22/2045 | Arecibo | PUR | Left | Right | 6' 3" | 180 lbs | - |
| Sanchez, Antonio | CF | Eureka Hornets | 19 | 04/22/2043 | San Juan | PUR | Switch | Right | 6' 1" | 180 lbs | - |
| Sanchez, Bobby | SP | Bighorn Bison | 19 | 06/28/2043 | San Francisco de Macorís | DOM | Left | Left | 6' 3" | 185 lbs | - |
| Sanchez, Carlos | RP | Dallas Texans | 18 | 05/12/2044 | Havana | CUB | Left | Left | 6' 4" | 195 lbs | - |
| Sanchez, Carlos | SP | Cairo Pharaohs | 19 | 06/01/2043 | Villa de Alvarez | MEX | Left | Right | 6' 3" | 175 lbs | - |
| Sanchez, Cesar | 1B | Kansas City Tornadoes | 19 | 11/24/2043 | Nezahualcoyotl | MEX | Left | Left | 6' 1" | 200 lbs | - |
| Sanchez, Daniel | SP | Cabo San Lucas Toreros | 18 | 01/25/2045 | Reynosa | MEX | Switch | Right | 6' 4" | 190 lbs | - |
| Sanchez, Daniel | SP | Pennsylvania Butterflies | 19 | 11/02/2043 | Mayagüez | PUR | Right | Right | 6' 4" | 185 lbs | - |
| Sanchez, Danny | CF | Asheville Moonshiners | 18 | 11/27/2044 | San Gregorio de Nigua | DOM | Right | Right | 6' 5" | 185 lbs | - |
| Sanchez, Danny | SP | Buffalo Bison | 18 | 07/27/2044 | Azcatepec | MEX | Right | Right | 6' 2" | 185 lbs | - |
| Sanchez, Dave | SP | El Paso Mavericks | 16 | 11/03/2046 | Santo Domingo | DOM | Left | Left | 5' 11" | 165 lbs | - |
| Sanchez, Eddie | SS | Free Agent | 22 | 01/26/2041 | Villa Fundación | DOM | Right | Right | 6' 1" | 180 lbs | - |
| Sanchez, Felipe | SP | Seattle Sasquatch | 17 | 06/28/2045 | Guayama | PUR | Left | Left | 5' 11" | 165 lbs | - |
| Sanchez, Frank | SP | Montreal Mounties | 16 | 03/24/2046 | Duvergé | DOM | Left | Right | 5' 11" | 160 lbs | - |
| Sanchez, Gerardo | RF | Montreal Jazz | 18 | 08/27/2044 | Las Yayas de Viajama | DOM | Left | Left | 6' 3" | 200 lbs | - |
| Sanchez, Izzy | SP | Buffalo Bison | 16 | 12/30/2046 | Puebla | MEX | Right | Right | 6' 2" | 180 lbs | - |
| Sanchez, Jerry | SP | Kansas City Tornadoes | 19 | 01/24/2044 | Arroyo Salado | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Sanchez, Jesus | SP | San Francisco Earthquakes | 18 | 12/14/2044 | Havana | CUB | Right | Right | 6' 8" | 200 lbs | - |
| Sanchez, Jesus | RP | Cairo Pharaohs | 23 | 09/07/2039 | Santa Catarina del Monte | MEX | Right | Right | 6' 8" | 220 lbs | $600,000 |
| Sanchez, Jonathan | RF | Maple Marauders | 26 | 09/15/2036 | Guarenas | VEN | Right | Left | 6' 3" | 200 lbs | $600,000 |
| Sanchez, Jordan | SP | Free Agent | 18 | 08/10/2044 | Guaynabo | PUR | Left | Left | 6' 0" | 170 lbs | - |
| Sanchez, Jorge | CF | Havana Stogies | 16 | 06/28/2046 | Higüey | DOM | Left | Right | 5' 11" | 175 lbs | - |
| Sanchez, Jorge | 2B | Asheville Moonshiners | 18 | 03/13/2044 | Río Grande | PUR | Switch | Right | 6' 1" | 180 lbs | - |
| Sanchez, Jorge | 3B | Free Agent | 19 | 10/04/2043 | El Tamarindo | MEX | Right | Right | 6' 1" | 185 lbs | - |
| Sanchez, Jose | SP | Cairo Pharaohs | 18 | 06/28/2044 | Río Grande | PUR | Switch | Right | 6' 5" | 195 lbs | - |
| Sanchez, Leo | SP | Walnut Creek Warriors | 16 | 05/21/2046 | San Juan | PUR | Right | Right | 6' 0" | 170 lbs | - |
| Sanchez, Leo | SP | Dallas Texans | 19 | 08/27/2043 | Havana | CUB | Right | Right | 6' 4" | 200 lbs | - |
| Sanchez, Marco | SP | Havana Stogies | 19 | 11/09/2043 | San Juan | PUR | Right | Right | 6' 1" | 175 lbs | - |
| Sanchez, Mauricio | LF | Cabo San Lucas Toreros | 19 | 09/07/2043 | Caguas | PUR | Left | Right | 6' 6" | 225 lbs | - |
| Sanchez, Melvin | SP | Free Agent | 17 | 08/14/2045 | Santo Domingo | DOM | Left | Left | 5' 9" | 160 lbs | - |
| Sanchez, Miguel | SP | Manhattan Slice | 18 | 01/29/2045 | Santiago de Cuba | CUB | Left | Left | 6' 0" | 175 lbs | - |
| Sanchez, Orlando | SP | Kansas City Tornadoes | 19 | 12/17/2043 | Havana | CUB | Left | Left | 6' 3" | 185 lbs | - |
| Sanchez, Rafael | LF | Dallas Texans | 18 | 05/24/2044 | Mexico City | MEX | Switch | Right | 6' 1" | 190 lbs | - |
| Sanchez, Rafael | RP | Free Agent | 18 | 09/05/2044 | Corozal | PUR | Right | Right | 5' 10" | 165 lbs | - |
| Sanchez, Ramon | SP | Bighorn Bison | 17 | 06/26/2045 | Loíza | PUR | Right | Right | 6' 1" | 170 lbs | - |
| Sanchez, Raul | 3B | Cairo Pharaohs | 16 | 11/11/2046 | Tlahuelilpan | MEX | Right | Right | 6' 0" | 175 lbs | - |
| Sanchez, Ricardo | 3B | Pennsylvania Butterflies | 19 | 07/09/2043 | San Antonio de los Baños | CUB | Right | Right | 6' 0" | 200 lbs | - |
| Sanchez, Ricky | SP | Walnut Creek Warriors | 17 | 12/09/2045 | Cuichapa | MEX | Switch | Right | 6' 2" | 185 lbs | - |
| Sanchez, Ricky | SP | Kansas City Tornadoes | 17 | 05/01/2045 | Caracas | VEN | Right | Right | 6' 6" | 195 lbs | - |
| Sanchez, Ricky | SP | Free Agent | 18 | 03/17/2044 | Matanzas | CUB | Right | Right | 6' 0" | 165 lbs | - |
| Sanchez, Rico | SP | Free Agent | 18 | 01/03/2045 | Caracas | VEN | Right | Right | 6' 2" | 175 lbs | - |
| Sanchez, Tony | LF | Free Agent | 17 | 07/25/2045 | San Juan | PUR | Right | Right | 6' 0" | 195 lbs | - |
| Sanchez, Tony | SP | Maple Marauders | 18 | 01/15/2045 | Havana | CUB | Right | Right | 6' 2" | 175 lbs | - |
| Sanchez, Willie | SP | Montreal Jazz | 17 | 12/14/2045 | Ponce | PUR | Right | Right | 6' 1" | 180 lbs | - |
| Sanchez, Willie | SP | Seattle Sasquatch | 17 | 08/16/2045 | San Cristóbal de las Casas | MEX | Left | Left | 6' 2" | 175 lbs | - |
| Sanchez, Willie | 3B | Asheville Moonshiners | 19 | 12/02/2043 | Santo Domingo | DOM | Right | Right | 6' 2" | 190 lbs | - |
| Sander, Nick | 1B | Cairo Pharaohs | 23 | 11/25/2039 | Chicago | USA | Left | Left | 6' 0" | 205 lbs | $600,000 |
| Sanders, Jason | SP | Eagle Rock Ridge Runners | 28 | 03/12/2034 | Springville | USA | Switch | Right | 6' 8" | 200 lbs | $10,600,000 |
| Sanders, Kelly | CF | Free Agent | 24 | 01/11/2039 | Norwalk | USA | Switch | Right | 6' 0" | 195 lbs | - |
| Sanderson, Austin | SP | Walnut Creek Warriors | 19 | 01/02/2044 | Siheung | KOR | Right | Right | 6' 5" | 180 lbs | - |
| Sandoval, Alex | SP | Seattle Sasquatch | 17 | 12/14/2045 | Carolina | PUR | Right | Right | 5' 11" | 170 lbs | - |
| Sandoval, Alex | SS | Dallas Texans | 18 | 10/14/2044 | Lajas | PUR | Right | Right | 6' 1" | 175 lbs | - |
| Sandoval, Alfredo | SP | Eureka Hornets | 16 | 03/19/2046 | Santiago de Cuba | CUB | Right | Right | 5' 10" | 150 lbs | - |
| Sandoval, Armando | 1B | Eagle Rock Ridge Runners | 16 | 11/03/2046 | Querétaro | MEX | Left | Left | 6' 8" | 240 lbs | - |
| Sandoval, Bill | SP | Hawaii Honu | 18 | 08/08/2044 | San Francisco de Macorís | DOM | Right | Right | 6' 0" | 170 lbs | - |
| Sandoval, Danny | CF | Buffalo Bison | 19 | 10/25/2043 | Vega Baja | PUR | Left | Left | 6' 2" | 175 lbs | - |
| Sandoval, Edwin | C | Montreal Jazz | 16 | 02/06/2046 | Constanza | DOM | Right | Right | 6' 1" | 190 lbs | - |
| Sandoval, Jerry | CF | Jacksonville Pilots | 19 | 01/19/2044 | Mexico City | MEX | Left | Left | 6' 2" | 180 lbs | - |
| Sandoval, Jose | SS | Manhattan Slice | 19 | 11/27/2043 | Humacao | PUR | Right | Right | 6' 0" | 160 lbs | - |
| Sandoval, Juan | SP | Quebec Armada | 17 | 07/10/2045 | Fajardo | PUR | Switch | Right | 6' 3" | 180 lbs | - |
| Sandoval, Ricky | RP | El Paso Mavericks | 17 | 03/05/2045 | Santiago | DOM | Right | Right | 6' 2" | 170 lbs | - |
| Sandoval, Vinny | SP | Kansas City Tornadoes | 18 | 08/30/2044 | Mexico City | MEX | Switch | Right | 5' 8" | 145 lbs | - |
| Sanguinacco, Livio | C | Maple Marauders | 18 | 05/15/2044 | Cabimas | VEN | Right | Right | 6' 4" | 200 lbs | - |
| Sano, Fujio | SP | Seattle Sasquatch | 16 | 03/25/2046 | Koshi | JPN | Left | Left | 6' 3" | 180 lbs | - |
| Sano, Sadakuno | SP | San Francisco Earthquakes | 20 | 11/14/2042 | Tono | JPN | Right | Right | 6' 6" | 200 lbs | - |
| Santa Cruz, Damian | LF | Eureka Hornets | 18 | 10/08/2044 | Santiago de Cuba | CUB | Left | Right | 6' 5" | 210 lbs | - |
| Santa Maria, Israel | CF | Maple Marauders | 19 | 11/20/2043 | El Tocuyo | VEN | Right | Right | 6' 3" | 200 lbs | - |
| Santamaria, Roberto | SS | Havana Stogies | 34 | 03/29/2028 | Guatemala | GUA | Switch | Right | 6' 3" | 200 lbs | $12,000,000 |
| Santana, Alberto | SP | Quebec Armada | 16 | 09/26/2046 | Guantanamo | CUB | Left | Left | 6' 2" | 180 lbs | - |
| Santana, Ernie | SP | Mexico City Luchadores | 17 | 10/03/2045 | Contla | MEX | Left | Left | 6' 4" | 185 lbs | - |
| Santaniello, Roy | LF | Bighorn Bison | 23 | 03/22/2039 | Okawville | USA | Left | Left | 6' 2" | 175 lbs | $600,000 |
| Santiago, Alex | SP | Vancouver Pioneers | 17 | 06/07/2045 | Guaynabo | PUR | Right | Right | 6' 0" | 170 lbs | - |
| Santiago, Angelo | SP | Buffalo Bison | 20 | 12/10/2042 | Santiago de Cuba | CUB | Right | Right | 6' 3" | 185 lbs | - |
| Santiago, Carlos | CF | Asheville Moonshiners | 16 | 06/08/2046 | Cardenas | CUB | Right | Right | 6' 1" | 175 lbs | - |
| Santiago, Francisco | SP | Bighorn Bison | 19 | 11/20/2043 | Santo Domingo | DOM | Right | Right | 6' 8" | 200 lbs | - |
| Santiago, Francisco | SP | Free Agent | 27 | 06/29/2035 | Guadalupe | MEX | Left | Right | 6' 7" | 200 lbs | - |
| Santiago, Jaime | CF | Mexico City Luchadores | 19 | 07/18/2043 | Carolina | PUR | Left | Right | 6' 1" | 170 lbs | - |
| Santiago, Jonas | CF | Cairo Pharaohs | 17 | 12/27/2045 | Puerto Vallarta | MEX | Left | Left | 6' 2" | 185 lbs | - |
| Santiago, Rafael | SS | Hawaii Honu | 27 | 12/03/2035 | Wilsonville | USA | Left | Right | 5' 10" | 190 lbs | $17,000,000 |
| Santiago, Ramon | RF | Pennsylvania Butterflies | 17 | 07/17/2045 | Santo Domingo | DOM | Left | Left | 6' 6" | 215 lbs | - |
| Santiago, Sal | SP | Jacksonville Pilots | 19 | 12/08/2043 | San Felipe | MEX | Right | Right | 5' 11" | 165 lbs | - |
| Santiago, Victor | 2B | Seattle Sasquatch | 18 | 04/20/2044 | Santiago de Cuba | CUB | Right | Right | 6' 1" | 175 lbs | - |
| Santiago, Willis | SP | Cairo Pharaohs | 19 | 08/12/2043 | Ocoyoacac | MEX | Left | Left | 6' 1" | 180 lbs | - |
| Santillanes, Carlos | 3B | Montreal Mounties | 18 | 10/04/2044 | Juncos | PUR | Right | Right | 6' 2" | 200 lbs | - |
| Santis, Luis | SS | Montreal Jazz | 18 | 10/10/2044 | Unión de Reyes | CUB | Right | Right | 6' 2" | 190 lbs | - |
| Santizo, Luis | 1B | Bloomington Blazers | 26 | 11/06/2036 | Jagüey Grande | CUB | Left | Right | 6' 4" | 200 lbs | $2,500,000 |
| Santizo, Oscar | 3B | Dallas Texans | 17 | 03/05/2045 | León | MEX | Right | Right | 6' 4" | 195 lbs | - |
| Santos, Billy | 3B | Eagle Rock Ridge Runners | 32 | 03/25/2030 | Cienfuegos | CUB | Right | Right | 5' 11" | 200 lbs | $1,500,000 |
| Santos, Edwin | C | Cabo San Lucas Toreros | 20 | 10/28/2042 | San Juan | PUR | Switch | Right | 6' 4" | 210 lbs | - |
| Santos, Gil | 2B | Pennsylvania Butterflies | 19 | 01/15/2044 | Santo Domingo | DOM | Right | Right | 6' 4" | 205 lbs | - |
| Santos, Javier | C | El Paso Mavericks | 17 | 09/04/2045 | Neyba | DOM | Right | Right | 6' 2" | 205 lbs | - |
| Santos, Jesus | SP | Montreal Mounties | 17 | 07/26/2045 | Yauco | PUR | Left | Left | 6' 4" | 190 lbs | - |
| Santos, Lupe | RF | Montreal Jazz | 20 | 02/04/2043 | Sabana Grande | PUR | Switch | Left | 6' 1" | 175 lbs | - |
| Santos, Marty | SP | Jacksonville Pilots | 17 | 08/08/2045 | Camuy | PUR | Left | Right | 6' 3" | 190 lbs | - |
| Santos, Omar | SP | Free Agent | 22 | 12/26/2040 | San Juan | PUR | Right | Right | 6' 1" | 180 lbs | - |
| Santos, Tony | RP | Free Agent | 18 | 02/17/2044 | Ecatepec | MEX | Right | Right | 6' 8" | 200 lbs | - |
| Santoyo, DeMario | CF | Walnut Creek Warriors | 18 | 11/04/2044 | Ciego de Avila | CUB | Right | Right | 6' 4" | 200 lbs | - |
| Santoyo, Tony | 3B | Jacksonville Pilots | 16 | 02/11/2046 | Santiago | DOM | Right | Right | 6' 0" | 175 lbs | - |
| Sarabia, Frank | 2B | Houghton Gremlins | 19 | 12/27/2043 | Samana | DOM | Right | Right | 6' 0" | 165 lbs | - |
| Sarabia, Tony | RP | Pennsylvania Butterflies | 19 | 05/30/2043 | San Martín de las Piramides | MEX | Right | Right | 6' 3" | 190 lbs | - |
| Sariol, Rodolfo | CL | Buffalo Bison | 20 | 01/31/2043 | Teziutlan | MEX | Left | Right | 6' 3" | 190 lbs | - |
| Sarmiento, Carlos | LF | Eureka Hornets | 18 | 06/05/2044 | Sahagún | MEX | Left | Right | 6' 2" | 200 lbs | - |
| Sarmiento, Danny | SS | Eagle Rock Ridge Runners | 16 | 05/22/2046 | Cuautitlan Izcalli | MEX | Right | Right | 6' 1" | 165 lbs | - |
| Sartore, Ryan | RP | Eureka Hornets | 22 | 11/30/2040 | Boca Raton | USA | Left | Left | 6' 0" | 185 lbs | $600,000 |
| Sartores, Manuell | CF | Cabo San Lucas Toreros | 18 | 03/15/2044 | Valle de la Pascua | VEN | Right | Right | 6' 2" | 175 lbs | - |
| Sasaki, Katsuhiko | SP | Bighorn Bison | 19 | 11/02/2043 | Nagoya | JPN | Left | Left | 6' 6" | 195 lbs | - |
| Sasaki, Kichiro | 3B | Walnut Creek Warriors | 17 | 05/06/2045 | Ise | JPN | Right | Right | 6' 0" | 190 lbs | - |
| Sasaki, Ryo | SP | Havana Stogies | 16 | 08/26/2046 | Kishigawa | JPN | Switch | Right | 6' 0" | 170 lbs | - |
| Sasaki, Ryuusei | SP | Free Agent | 16 | 07/04/2046 | Tokyo | JPN | Left | Right | 6' 2" | 180 lbs | - |
| Sato, Masuhiro | SP | Jacksonville Pilots | 18 | 11/06/2044 | Kimitsu | JPN | Right | Right | 5' 11" | 165 lbs | - |
| Sato, Takatsugu | SP | Free Agent | 17 | 02/02/2046 | Kawagoe | JPN | Right | Right | 5' 11" | 165 lbs | - |
| Sato, Tatsuki | SP | Mexico City Luchadores | 18 | 09/09/2044 | Fuchu | JPN | Right | Right | 6' 3" | 180 lbs | - |
| Sato, Tomokazu | SP | Free Agent | 17 | 01/03/2046 | Kokubunji | JPN | Right | Right | 6' 1" | 170 lbs | - |
| Saucedo, Antonio | CF | San Francisco Earthquakes | 19 | 11/23/2043 | Apaseo el Alto | MEX | Left | Left | 6' 0" | 170 lbs | - |
| Saucedo, Damian | SP | Quebec Armada | 18 | 11/11/2044 | Maracaibo | VEN | Switch | Left | 6' 1" | 170 lbs | - |
| Saucedo, Juan | SP | Manhattan Slice | 19 | 08/09/2043 | Bonao | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Saucedo, Miguel | SP | Cairo Pharaohs | 17 | 10/04/2045 | La Vega | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Saunderson, Bryce | SS | Dallas Texans | 18 | 08/22/2044 | Hampden | AUS | Right | Right | 6' 2" | 185 lbs | - |
| Savinon, Luis | LF | Free Agent | 17 | 05/11/2045 | Chihuahua | MEX | Right | Right | 5' 10" | 185 lbs | - |
| Savona, Eric | RP | Vancouver Pioneers | 24 | 12/21/2038 | Lincolnwood | USA | Left | Left | 6' 3" | 200 lbs | $600,000 |
| Sawyer, Chris | CF | Dallas Texans | 24 | 12/23/2038 | Niles | USA | Right | Right | 6' 6" | 200 lbs | $1,200,000 |
| Sawyer, Cody | C | Free Agent | 25 | 10/10/2037 | Los Angeles | USA | Right | Right | 6' 0" | 195 lbs | - |
| Saxton, Matt | LF | Walnut Creek Warriors | 20 | 09/25/2042 | Salem | USA | Right | Right | 6' 3" | 180 lbs | $600,000 |
| Scala, Edgar | RP | Free Agent | 17 | 04/29/2045 | Barinas | VEN | Left | Right | 6' 4" | 180 lbs | - |
| Schaefer, Matt | RF | Walnut Creek Warriors | 20 | 03/18/2042 | Dunedin | USA | Left | Left | 6' 3" | 185 lbs | $600,000 |
| Schauder, Chris | RF | Milwaukee Millers | 22 | 04/21/2040 | Staten Island | USA | Switch | Right | 6' 6" | 200 lbs | $600,000 |
| Scheid, Mike | RP | Manhattan Slice | 29 | 03/28/2033 | Kenosha | USA | Switch | Right | 6' 0" | 200 lbs | $7,900,000 |
| Schimmel, Jonathan | RF | Buffalo Bison | 22 | 02/14/2040 | San Antonio | USA | Right | Right | 6' 2" | 185 lbs | $600,000 |
| Schroeder, Nick | LF | Chicago Eclipse | 24 | 01/05/2039 | Delray Beach | USA | Right | Right | 6' 6" | 205 lbs | $600,000 |
| Schuler, Christoph | 2B | Eagle Rock Ridge Runners | 16 | 07/03/2046 | Ahrensburg | GER | Right | Right | 6' 1" | 185 lbs | - |
| Schuss, Rob | RP | Montreal Mounties | 25 | 11/10/2037 | Prairie Village | USA | Right | Right | 6' 6" | 200 lbs | $600,000 |
| Schutt, Andy | RP | Havana Stogies | 23 | 07/04/2039 | West Babylon | USA | Right | Right | 6' 0" | 175 lbs | $1,623,000 |
| Scolari, Andres | RP | Dallas Texans | 17 | 02/25/2045 | Puerto Ayacucho | VEN | Right | Right | 6' 8" | 200 lbs | - |
| Scolari, Orfeo | SP | Free Agent | 16 | 09/24/2046 | Puerto Cabello | VEN | Right | Right | 6' 5" | 195 lbs | - |
| Scorsese, Cirillo | SP | Chicago Eclipse | 18 | 09/08/2044 | Maracaibo | VEN | Switch | Left | 6' 4" | 190 lbs | - |
| Scott, Justin | LF | Manhattan Slice | 24 | 05/29/2038 | Lakeville | USA | Right | Left | 6' 3" | 200 lbs | $1,200,000 |
| Scott, Sam | RP | Maple Marauders | 24 | 07/01/2038 | South Laurel | USA | Right | Right | 6' 6" | 200 lbs | $600,000 |
| Scott, Steve | RF | Free Agent | 26 | 06/04/2036 | Bullhead City | USA | Left | Left | 5' 11" | 180 lbs | - |
| Seare, Wayne | SS | Bighorn Bison | 31 | 07/02/2031 | Johannesburg | RSA | Right | Right | 6' 1" | 195 lbs | $1,700,000 |
| Sedano, Miguel | SP | Milwaukee Millers | 17 | 09/25/2045 | San Pedro los Baños | MEX | Left | Left | 6' 0" | 170 lbs | - |
| Segura, Abraham | SP | El Paso Mavericks | 16 | 12/14/2046 | Madero | MEX | Right | Left | 6' 0" | 170 lbs | - |
| Segura, Manny | SP | Vancouver Pioneers | 18 | 04/17/2044 | Las Guaranas | DOM | Switch | Right | 6' 5" | 190 lbs | - |
| Segura, Ray | 2B | Houghton Gremlins | 17 | 11/12/2045 | La Piedad | MEX | Left | Right | 6' 1" | 195 lbs | - |
| Seidler, Tobias | CF | Walnut Creek Warriors | 16 | 07/21/2046 | Vienna | AUT | Right | Right | 6' 1" | 170 lbs | - |
| Selby, Gary | SP | Montreal Mounties | 24 | 10/09/2038 | North Charleston | USA | Right | Right | 6' 2" | 195 lbs | $600,000 |
| Sells, Kyle | 3B | Seattle Sasquatch | 22 | 06/07/2040 | Reston | USA | Right | Right | 6' 0" | 170 lbs | $600,000 |
| Semones, Wilfrid | C | Free Agent | 24 | 04/12/2038 | Rhade | GER | Right | Right | 5' 10" | 190 lbs | - |
| Sena, Francis | 2B | Free Agent | 18 | 12/15/2044 | Carrizal | VEN | Right | Right | 6' 1" | 185 lbs | - |
| Senda, Ukon | 1B | Bloomington Blazers | 20 | 08/30/2042 | Toyama | JPN | Right | Right | 6' 3" | 205 lbs | - |
| Sensini, Biagio | SP | Free Agent | 37 | 01/27/2026 | Gassino Torinese | ITA | Right | Right | 6' 5" | 200 lbs | - |
| Seow, Gin-fan | SP | Montreal Jazz | 18 | 07/13/2044 | Kaohsiung | TPE | Right | Right | 6' 6" | 195 lbs | - |
| Sepulveda, Alex | CF | Kansas City Tornadoes | 19 | 04/06/2043 | Pachuca | MEX | Right | Right | 6' 0" | 200 lbs | - |
| Sepulveda, Hector | RP | Free Agent | 16 | 07/12/2046 | Mayagüez | PUR | Right | Right | 6' 4" | 190 lbs | - |
| Sepulveda, Melvin | SP | Seattle Sasquatch | 35 | 12/10/2027 | Ciego de Avila | CUB | Right | Right | 6' 1" | 195 lbs | $9,600,000 |
| Sepulveda, Oscar | 1B | Free Agent | 19 | 07/20/2043 | Bayamón | PUR | Left | Right | 6' 2" | 200 lbs | - |
| Sepulveda, Willie | RP | Free Agent | 17 | 02/11/2045 | San Juan | PUR | Right | Right | 6' 1" | 170 lbs | - |
| Sequeira, David | SP | Walnut Creek Warriors | 17 | 04/21/2045 | Cabo Rojo | PUR | Right | Right | 6' 2" | 185 lbs | - |
| Serna, Antonio | C | Houghton Gremlins | 18 | 06/26/2044 | Santo Domingo | DOM | Right | Right | 6' 2" | 200 lbs | - |
| Serna, Antonio | 2B | San Francisco Earthquakes | 20 | 12/18/2042 | Ajoloapan | MEX | Right | Right | 6' 1" | 185 lbs | - |
| Serna, Edwin | SP | El Paso Mavericks | 30 | 10/03/2032 | Arecibo | PUR | Right | Right | 6' 4" | 200 lbs | $9,600,000 |
| Serna, Elias | SP | Quebec Armada | 19 | 06/27/2043 | San Juan | PUR | Right | Right | 6' 7" | 195 lbs | - |
| Serna, Enrique | 2B | Jacksonville Pilots | 18 | 11/26/2044 | Mayagüez | PUR | Right | Right | 6' 4" | 185 lbs | - |
| Serna, Gustavo | SP | Mexico City Luchadores | 19 | 05/05/2043 | Colombia | CUB | Right | Right | 6' 1" | 175 lbs | - |
| Serna, Jose | LF | Free Agent | 17 | 05/08/2045 | Guantanamo | CUB | Right | Right | 6' 6" | 235 lbs | - |
| Serrano, Fernando | RP | Asheville Moonshiners | 17 | 11/04/2045 | Bayamón | PUR | Left | Right | 6' 2" | 175 lbs | - |
| Serrano, Julio | SP | Free Agent | 17 | 04/26/2045 | Jarabacoa | DOM | Right | Right | 5' 9" | 155 lbs | - |
| Serrano, Pedro | 3B | Free Agent | 19 | 10/12/2043 | Bayamón | PUR | Switch | Right | 5' 10" | 180 lbs | - |
| Serrano, Tony | RP | Free Agent | 17 | 01/27/2046 | Santa Clara | CUB | Switch | Right | 6' 1" | 170 lbs | - |
| Serrano, Vinny | SP | Asheville Moonshiners | 19 | 11/26/2043 | Comerío | PUR | Right | Right | 6' 3" | 180 lbs | - |
| Serrata, Ramon | SP | Hawaii Honu | 17 | 03/17/2045 | Havana | CUB | Left | Left | 6' 8" | 200 lbs | - |
| Serrata, Ruben | RP | Free Agent | 18 | 06/26/2044 | Tepexpan | MEX | Right | Right | 6' 4" | 185 lbs | - |
| Serrato, Alvaro | SP | Kansas City Tornadoes | 18 | 08/13/2044 | Bajos de Haina | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Serrato, Juan | SP | Kansas City Tornadoes | 18 | 11/01/2044 | Havana | CUB | Right | Right | 6' 5" | 195 lbs | - |
| Serrato, Juan | 3B | Free Agent | 33 | 05/19/2029 | Santiago | DOM | Right | Right | 6' 4" | 205 lbs | - |
| Serrato, Miguel | RF | Maple Marauders | 17 | 08/22/2045 | Mazatlan | MEX | Left | Left | 6' 2" | 205 lbs | - |
| Serrato, Willie | CF | Montreal Jazz | 16 | 05/06/2046 | Bayamo | CUB | Switch | Right | 6' 3" | 185 lbs | - |
| Serratos, Jesus | SP | Jacksonville Pilots | 17 | 01/19/2046 | Guayama | PUR | Left | Left | 6' 4" | 185 lbs | - |
| Servantes, Angelo | LF | Manhattan Slice | 18 | 08/29/2044 | Juana Díaz | PUR | Right | Right | 6' 2" | 200 lbs | - |
| Sevilla, Juan | SP | Free Agent | 18 | 02/10/2044 | Santo Domingo | DOM | Right | Right | 6' 1" | 180 lbs | - |
| Sevilla, Tony | 1B | Havana Stogies | 18 | 02/21/2044 | Calabozo | VEN | Right | Right | 6' 0" | 200 lbs | - |
| Sghir, Ghaysun | RP | San Francisco Earthquakes | 30 | 09/21/2032 | Graaff-Reinet | RSA | Switch | Right | 6' 5" | 205 lbs | - |
| Shackleton, Andrew | SP | Seattle Sasquatch | 29 | 04/20/2033 | Sint Michiel | CUR | Right | Right | 6' 2" | 195 lbs | $18,000,000 |
| Shaffer, Drew | SP | Free Agent | 35 | 06/19/2027 | Bedford | USA | Left | Left | 6' 1" | 200 lbs | - |
| Shanbhag, Apratipa | SP | Asheville Moonshiners | 17 | 11/18/2045 | Sopur | IND | Right | Right | 6' 0" | 170 lbs | - |
| Shanchez, Hector | SP | Free Agent | 17 | 04/16/2045 | Vega Baja | PUR | Switch | Right | 6' 8" | 200 lbs | - |
| Shaw, Bobby | LF | Pennsylvania Butterflies | 24 | 11/12/2038 | El Paso | USA | Left | Left | 6' 3" | 195 lbs | $600,000 |
| Shelton, Greg | C | Dallas Texans | 23 | 12/07/2039 | New York | USA | Right | Right | 6' 0" | 200 lbs | $600,000 |
| Shephard, Wenceslas | CF | Manhattan Slice | 19 | 01/13/2044 | Tariba | VEN | Right | Right | 6' 4" | 195 lbs | - |
| Sheppard, Chris | 3B | Montreal Jazz | 25 | 10/05/2037 | Neodesha | USA | Right | Right | 6' 0" | 190 lbs | $1,680,000 |
| Sherman, Jesse | LF | Free Agent | 17 | 06/06/2045 | Agoura Hills | USA | Left | Left | 6' 4" | 200 lbs | - |
| Sherrill, Stephen | LF | Walnut Creek Warriors | 25 | 05/01/2037 | The Hague | NED | Left | Left | 6' 4" | 200 lbs | $600,000 |
| Sherry, Jimmy | CL | Cabo San Lucas Toreros | 31 | 04/10/2031 | San Diego | USA | Right | Right | 6' 2" | 200 lbs | $9,300,000 |
| Shewman, Bobby | RP | Free Agent | 19 | 11/14/2043 | Los Angeles | USA | Left | Left | 6' 3" | 185 lbs | - |
| Shiba, Akiho | C | Free Agent | 18 | 02/16/2044 | Kasugai | JPN | Switch | Right | 6' 2" | 190 lbs | - |
| Shibata, Hisatomo | SP | Montreal Jazz | 16 | 03/05/2046 | Kanazawa | JPN | Right | Right | 6' 0" | 165 lbs | - |
| Shields Jr., Tim | LF | Free Agent | 28 | 02/24/2034 | New York | USA | Right | Right | 6' 3" | 200 lbs | - |
| Shifflet, Jared | 3B | Cairo Pharaohs | 29 | 08/17/2033 | Oracle | USA | Right | Right | 6' 4" | 205 lbs | $3,328,000 |
| Shigemura, Katsuharu | LF | Maple Marauders | 16 | 01/17/2047 | Minokamo | JPN | Left | Right | 5' 10" | 160 lbs | - |
| Shima, Hiroiaki | SP | Montreal Jazz | 17 | 02/12/2045 | Matsusaka | JPN | Left | Left | 6' 1" | 180 lbs | - |
| Shimabukuro, Junichi | RP | El Paso Mavericks | 17 | 09/28/2045 | Shiroi | JPN | Left | Left | 6' 4" | 185 lbs | - |
| Shimabukuro, Tatsuaki | SP | Cairo Pharaohs | 18 | 10/01/2044 | Otsu | JPN | Left | Left | 6' 0" | 175 lbs | - |
| Shimizu, Kasutashi | SP | Eureka Hornets | 17 | 12/05/2045 | Hashima | JPN | Right | Right | 6' 4" | 180 lbs | - |
| Shimizu, Korin | SP | Walnut Creek Warriors | 17 | 06/02/2045 | Ichihara | JPN | Right | Right | 6' 2" | 180 lbs | - |
| Shimizu, Rikyu | 1B | Buffalo Bison | 19 | 06/03/2043 | Koshigaya | JPN | Right | Right | 6' 4" | 200 lbs | - |
| Shimokawa, Nijiya | SP | Free Agent | 20 | 04/10/2042 | Nagano | JPN | Right | Right | 5' 11" | 170 lbs | - |
| Shin, Dae-il | LF | Free Agent | 21 | 09/24/2041 | Gwangmyeong | KOR | Left | Left | 6' 3" | 200 lbs | - |
| Shin, Jeong | SP | Jacksonville Pilots | 19 | 08/27/2043 | Daegu | KOR | Left | Left | 5' 11" | 165 lbs | - |
| Shin, Jin-haeng | SP | Jacksonville Pilots | 18 | 10/31/2044 | Goyang | KOR | Left | Left | 6' 1" | 175 lbs | - |
| Shiplack, Steven | RP | Asheville Moonshiners | 31 | 08/30/2031 | Toronto | CAN | Right | Right | 6' 2" | 200 lbs | $4,366,200 |
| Shiraishi, Daisuke | CF | Walnut Creek Warriors | 17 | 10/13/2045 | Kashiba | JPN | Right | Right | 6' 5" | 200 lbs | - |
| Shishido, Kimio | SP | Milwaukee Millers | 17 | 08/09/2045 | Fukuoka | JPN | Right | Right | 6' 5" | 190 lbs | - |
| Sho, Dong-joo | 2B | San Francisco Earthquakes | 18 | 03/31/2044 | Busan | KOR | Left | Right | 6' 0" | 165 lbs | - |
| Shon, Byung-ho | SP | Free Agent | 18 | 04/08/2044 | Icheon | KOR | Left | Right | 6' 6" | 195 lbs | - |
| Shook, Bill | CF | Pennsylvania Butterflies | 23 | 09/03/2039 | Toronto | CAN | Right | Right | 6' 2" | 190 lbs | $3,264,000 |
| Shook, Kerwin | RF | Free Agent | 28 | 07/21/2034 | Dunblane | CAN | Left | Left | 6' 2" | 200 lbs | - |
| Shope, Billy | RF | Free Agent | 23 | 09/01/2039 | Toms River | USA | Left | Left | 6' 5" | 200 lbs | - |
| Shuai, Hua-ding | SP | Pennsylvania Butterflies | 19 | 12/07/2043 | Luchou | TPE | Right | Right | 6' 5" | 200 lbs | - |
| Shui, Gin-fan | 3B | Buffalo Bison | 18 | 08/20/2044 | Taichung | TPE | Right | Right | 6' 1" | 185 lbs | - |
| Sibiga, Jonathan | 2B | Mexico City Luchadores | 24 | 07/21/2038 | Austin | USA | Right | Right | 6' 3" | 205 lbs | $600,000 |
| Sibrian, Danny | RP | El Paso Mavericks | 17 | 12/02/2045 | Tamayo | DOM | Right | Right | 6' 3" | 180 lbs | - |
| Sical, Andres | LF | Cabo San Lucas Toreros | 17 | 03/13/2045 | Bogota | COL | Right | Right | 6' 2" | 205 lbs | - |
| Sierra, Francisco | 3B | San Francisco Earthquakes | 18 | 11/18/2044 | Santo Domingo | DOM | Right | Right | 6' 3" | 190 lbs | - |
| Sierra, Leo | RP | Hawaii Honu | 16 | 11/16/2046 | Palmira | CUB | Right | Right | 6' 0" | 170 lbs | - |
| Sierra, Luis | CF | Montreal Mounties | 19 | 11/07/2043 | San Juan | PUR | Right | Right | 6' 4" | 190 lbs | - |
| Sierra, Manny | C | Milwaukee Millers | 17 | 09/25/2045 | Guaymas | MEX | Right | Right | 6' 1" | 190 lbs | - |
| Sierra, Michael | SS | Maple Marauders | 18 | 01/27/2045 | Santo Domingo | DOM | Left | Right | 6' 2" | 165 lbs | - |
| Sierra, Orlando | C | Dallas Texans | 18 | 05/21/2044 | Ceiba | PUR | Switch | Right | 6' 2" | 185 lbs | - |
| Sierra, Pedro | SP | San Francisco Earthquakes | 19 | 08/26/2043 | Maracaibo | VEN | Right | Right | 6' 2" | 180 lbs | - |
| Sierra, Tony | CF | Montreal Jazz | 19 | 06/17/2043 | Canóvanas | PUR | Right | Right | 6' 5" | 195 lbs | - |
| Sierra, Willie | CF | Cairo Pharaohs | 18 | 05/13/2044 | Sancti Spíritus | CUB | Left | Left | 6' 0" | 180 lbs | - |
| Sifuentes, Francisco | 2B | Free Agent | 21 | 12/25/2041 | Mayagüez | PUR | Right | Right | 6' 2" | 185 lbs | - |
| Sifuentes, Henry | SP | Quebec Armada | 19 | 10/11/2043 | Havana | CUB | Right | Right | 6' 2" | 175 lbs | - |
| Sillas, Danny | LF | Free Agent | 18 | 07/11/2044 | Aguascalientes | MEX | Right | Right | 6' 4" | 200 lbs | - |
| Silva, Alex | 2B | Quebec Armada | 20 | 12/22/2042 | La Vega | DOM | Right | Right | 5' 10" | 175 lbs | - |
| Silva, Angelo | SP | Free Agent | 20 | 03/19/2042 | Utuado | PUR | Right | Right | 6' 3" | 180 lbs | - |
| Silva, Bruce | SP | Montreal Jazz | 19 | 09/08/2043 | Carolina | PUR | Right | Right | 6' 0" | 170 lbs | - |
| Silva, Eddie | RF | Maple Marauders | 27 | 04/05/2035 | Santa Rosalía | MEX | Left | Left | 6' 6" | 200 lbs | $600,000 |
| Silva, Edgar | RP | Vancouver Pioneers | 18 | 07/03/2044 | Río Cauto | CUB | Left | Left | 6' 1" | 175 lbs | - |
| Silva, Javy | RP | Cabo San Lucas Toreros | 16 | 02/26/2046 | Mao | DOM | Right | Right | 6' 2" | 170 lbs | - |
| Silva, Jorge | SS | Montreal Mounties | 19 | 09/11/2043 | Mayagüez | PUR | Switch | Right | 6' 2" | 180 lbs | - |
| Silva, Jose | SP | Mexico City Luchadores | 16 | 08/18/2046 | Maracaibo | VEN | Left | Right | 6' 1" | 175 lbs | - |
| Silva, Jose | SP | San Francisco Earthquakes | 17 | 11/19/2045 | La Vega | DOM | Left | Right | 6' 6" | 200 lbs | - |
| Silva, Jose | 1B | Mexico City Luchadores | 17 | 04/14/2045 | Havana | CUB | Right | Right | 6' 5" | 225 lbs | - |
| Silva, Luis | CF | Milwaukee Millers | 17 | 03/30/2045 | San Luis | CUB | Left | Left | 6' 3" | 180 lbs | - |
| Silva, Manny | LF | Manhattan Slice | 17 | 05/01/2045 | San Juan | PUR | Left | Right | 6' 1" | 190 lbs | - |
| Silva, Melvin | CF | Montreal Jazz | 19 | 07/18/2043 | Cayey | PUR | Right | Right | 6' 2" | 180 lbs | - |
| Silva, Robert | SP | Chicago Eclipse | 16 | 07/24/2046 | Mérida | MEX | Right | Right | 6' 5" | 190 lbs | - |
| Silvas, Gabe | SP | Chicago Eclipse | 19 | 04/03/2043 | Maracay | VEN | Switch | Left | 6' 1" | 175 lbs | - |
| Silvestre, David | C | Free Agent | 19 | 06/30/2043 | Guaynabo | PUR | Right | Right | 6' 0" | 200 lbs | - |
| Sima, Mei-shio | SP | Vancouver Pioneers | 18 | 04/23/2044 | Taichung | TPE | Right | Right | 6' 6" | 195 lbs | - |
| Simai, Ethan | RF | Hawaii Honu | 16 | 02/25/2046 | Lichtenburg | RSA | Left | Left | 6' 1" | 180 lbs | - |
| Simmons, Jamal | 1B | Vancouver Pioneers | 23 | 11/25/2039 | Livonia | USA | Right | Right | 6' 2" | 200 lbs | $600,000 |
| Simmons, Steve | C | Seattle Sasquatch | 24 | 03/10/2038 | Citrus Heights | USA | Right | Right | 5' 10" | 195 lbs | $600,000 |
| Simmons, Tom | SP | Manhattan Slice | 31 | 01/29/2032 | Ajax | CAN | Left | Left | 6' 8" | 200 lbs | $11,000,000 |
| Simms, Jared | SP | Bloomington Blazers | 25 | 07/05/2037 | Chicago | USA | Left | Left | 6' 9" | 205 lbs | $2,600,000 |
| Simon, Ethan | C | Jacksonville Pilots | 18 | 07/24/2044 | Eggenfelden | GER | Right | Right | 6' 4" | 200 lbs | - |
| Simpson, Kiminobu | C | Free Agent | 22 | 11/09/2040 | Kawasaki | JPN | Right | Right | 6' 1" | 190 lbs | - |
| Sirias, Jordan | SP | San Francisco Earthquakes | 18 | 09/23/2044 | Palma Soriano | CUB | Right | Right | 6' 5" | 185 lbs | - |
| Sisneros, Javier | SP | Free Agent | 17 | 06/02/2045 | Puerto Plata | DOM | Right | Right | 6' 3" | 180 lbs | - |
| Slader, Zach | CF | Free Agent | 23 | 10/26/2039 | Great Falls | USA | Right | Right | 6' 1" | 190 lbs | - |
| Slama, Simon | SP | Kansas City Tornadoes | 24 | 05/19/2038 | Marion | USA | Left | Left | 6' 2" | 200 lbs | $600,000 |
| Sljivancanin, Gavrilo | CF | Kansas City Tornadoes | 18 | 07/17/2044 | Sofia | BUL | Left | Left | 6' 1" | 175 lbs | - |
| Smith, Isaiah | SS | Free Agent | 30 | 10/08/2032 | Gilmore | USA | Right | Right | 5' 9" | 200 lbs | - |
| Smith, James | C | Mexico City Luchadores | 30 | 10/06/2032 | Richmond | USA | Left | Right | 6' 0" | 200 lbs | $600,000 |
| Smith, Jayden | SP | Free Agent | 34 | 05/25/2028 | Manassas | USA | Right | Right | 6' 2" | 195 lbs | - |
| Snell, Grant | SS | Mexico City Luchadores | 27 | 02/25/2035 | Bellevue | USA | Right | Right | 6' 1" | 185 lbs | $1,100,000 |
| Snyder, David | SP | Free Agent | 30 | 11/04/2032 | Tokyo | JPN | Right | Right | 6' 1" | 200 lbs | - |
| Socorro, Tony | SP | Eureka Hornets | 17 | 06/02/2045 | Guantanamo | CUB | Right | Right | 6' 4" | 185 lbs | - |
| Solano, Bobby | C | Seattle Sasquatch | 18 | 10/25/2044 | Bayamo | CUB | Right | Right | 6' 6" | 220 lbs | - |
| Solano, Jonathan | SP | Buffalo Bison | 31 | 11/30/2031 | Santiago | DOM | Left | Right | 6' 2" | 200 lbs | $600,000 |
| Solano, Victor | SP | Hawaii Honu | 18 | 06/15/2044 | Cueto | CUB | Left | Left | 6' 4" | 180 lbs | - |
| Solares, Pablo | SP | Mexico City Luchadores | 16 | 02/25/2046 | San Francisco de Macorís | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Soler, Dave | 1B | Pennsylvania Butterflies | 16 | 10/20/2046 | Neyba | DOM | Left | Left | 6' 2" | 195 lbs | - |
| Soler, Jordan | CF | Kansas City Tornadoes | 17 | 03/04/2045 | Havana | CUB | Right | Right | 6' 1" | 175 lbs | - |
| Solis, Alex | SP | Free Agent | 36 | 11/15/2026 | Santo Domingo | DOM | Right | Right | 6' 4" | 200 lbs | - |
| Solis, Alfredo | RP | Free Agent | 18 | 04/06/2044 | Bayamón | PUR | Left | Left | 6' 2" | 180 lbs | - |
| Solis, Carlos | RF | Eureka Hornets | 18 | 09/30/2044 | Río Grande | PUR | Left | Left | 6' 4" | 205 lbs | - |
| Solis, Estevan | SP | Vancouver Pioneers | 18 | 11/18/2044 | Peralta | DOM | Left | Left | 5' 10" | 165 lbs | - |
| Solis, Fidel | C | Asheville Moonshiners | 18 | 01/14/2045 | Concepción Jolalpan | MEX | Left | Right | 6' 4" | 200 lbs | - |
| Solis, Franklin | CF | Dallas Texans | 17 | 06/28/2045 | Puerto Plata | DOM | Right | Right | 5' 11" | 160 lbs | - |
| Solis, Mario | SP | Pennsylvania Butterflies | 24 | 06/24/2038 | Mexico City | MEX | Left | Left | 6' 1" | 190 lbs | $600,000 |
| Solis, Ray | SP | Vancouver Pioneers | 18 | 09/11/2044 | Carolina | PUR | Right | Right | 6' 6" | 195 lbs | - |
| Solis, Ruben | RP | Free Agent | 18 | 07/06/2044 | Santo Domingo | DOM | Switch | Right | 6' 8" | 210 lbs | - |
| Soliz, Jose | SP | Montreal Mounties | 17 | 01/03/2046 | Chicoloapan | MEX | Left | Left | 6' 2" | 180 lbs | - |
| Solorio, Marco | 2B | Eureka Hornets | 19 | 06/27/2043 | Neyba | DOM | Switch | Right | 6' 0" | 175 lbs | - |
| Solorzano, Marco | SP | Walnut Creek Warriors | 17 | 12/22/2045 | Mexico City | MEX | Left | Left | 6' 0" | 175 lbs | - |
| Somerville, Xavier | CF | San Francisco Earthquakes | 20 | 01/06/2043 | Sydney | AUS | Right | Right | 6' 0" | 185 lbs | - |
| Sommerville, John | RP | Free Agent | 30 | 12/10/2032 | Streetsboro | USA | Switch | Right | 6' 3" | 200 lbs | - |
| Sone, Hiroyasu | SP | Havana Stogies | 18 | 07/12/2044 | Kagoshima | JPN | Right | Right | 6' 7" | 200 lbs | - |
| Soranzo, Bernardo | SP | Bighorn Bison | 18 | 06/16/2044 | La Victoria | VEN | Switch | Right | 6' 1" | 175 lbs | - |
| Soria, Orlando | SP | Eureka Hornets | 18 | 07/19/2044 | Camagüey | CUB | Left | Right | 6' 4" | 185 lbs | - |
| Soriano, Lorenzo | RF | Free Agent | 17 | 12/16/2045 | Querétaro | MEX | Left | Left | 6' 1" | 185 lbs | - |
| Soriano, Ricardo | 2B | Free Agent | 20 | 12/18/2042 | Bayamón | PUR | Right | Right | 6' 1" | 200 lbs | - |
| Sorrells, Miles | SP | Hawaii Honu | 23 | 04/25/2039 | Shelbyville | USA | Left | Left | 6' 2" | 190 lbs | $600,000 |
| Sosa, Carlos | 3B | Asheville Moonshiners | 26 | 06/05/2036 | Tulsa | USA | Right | Right | 6' 0" | 195 lbs | $600,000 |
| Sosa, Oscar | CF | Manhattan Slice | 18 | 09/22/2044 | General Escobedo | MEX | Right | Right | 6' 4" | 215 lbs | - |
| Sosa, Tony | C | Dallas Texans | 17 | 04/10/2045 | Santo Domingo | DOM | Left | Right | 6' 2" | 195 lbs | - |
| Sosaya, Vincent | SP | Montreal Mounties | 18 | 12/02/2044 | Chihuahua | MEX | Switch | Right | 6' 3" | 185 lbs | - |
| Sotello, Raul | LF | Free Agent | 16 | 09/20/2046 | Hatillo | PUR | Left | Left | 6' 2" | 190 lbs | - |
| Sotelo, Angelo | SP | Mexico City Luchadores | 18 | 04/27/2044 | Chilpancingo | MEX | Switch | Right | 6' 4" | 190 lbs | - |
| Soto, Alvaro | CL | El Paso Mavericks | 17 | 04/28/2045 | Matamoros | MEX | Switch | Right | 5' 11" | 155 lbs | - |
| Soto, Andres | SP | Cairo Pharaohs | 17 | 05/16/2045 | Santo Domingo | DOM | Left | Left | 6' 3" | 180 lbs | - |
| Soto, Antonio | RP | Free Agent | 17 | 08/28/2045 | Vieques | PUR | Left | Left | 6' 1" | 170 lbs | - |
| Soto, Billy | C | Montreal Mounties | 19 | 08/03/2043 | Manizales | COL | Switch | Right | 6' 1" | 190 lbs | - |
| Soto, Cortez | SP | Montreal Mounties | 17 | 05/01/2045 | Caguas | PUR | Right | Right | 6' 6" | 200 lbs | - |
| Soto, Danny | RP | Free Agent | 17 | 11/25/2045 | Izúcar | MEX | Right | Right | 6' 2" | 180 lbs | - |
| Soto, Danny | SP | Milwaukee Millers | 17 | 06/06/2045 | Santa Cruz del Sur | CUB | Right | Right | 5' 10" | 165 lbs | - |
| Soto, Jairo | 1B | Free Agent | 17 | 04/21/2045 | Los Ríos | DOM | Right | Right | 6' 9" | 235 lbs | - |
| Soto, Jesus | 2B | Quebec Armada | 18 | 03/10/2044 | Ponce | PUR | Right | Right | 6' 2" | 190 lbs | - |
| Soto, Jose | 2B | Quebec Armada | 16 | 03/31/2046 | La Romana | DOM | Right | Right | 6' 1" | 195 lbs | - |
| Soto, Jose | 3B | Asheville Moonshiners | 16 | 04/23/2046 | Palo Negro | VEN | Switch | Right | 6' 2" | 195 lbs | - |
| Soto, Jose | SS | Free Agent | 18 | 06/24/2044 | Mexico City | MEX | Right | Right | 6' 0" | 175 lbs | - |
| Soto, Juan | RF | Chicago Eclipse | 19 | 08/10/2043 | Camargo | MEX | Left | Left | 6' 1" | 190 lbs | - |
| Soto, Luis | LF | Bloomington Blazers | 18 | 06/15/2044 | San Juan | PUR | Right | Right | 6' 5" | 205 lbs | - |
| Soto, Manny | SP | Chicago Eclipse | 18 | 06/27/2044 | Trujillo Alto | PUR | Switch | Left | 6' 2" | 180 lbs | - |
| Soto, Miguel | 3B | Cabo San Lucas Toreros | 19 | 08/27/2043 | Tlaquepaque | MEX | Right | Right | 6' 1" | 190 lbs | - |
| Soto, Ramon | C | Free Agent | 17 | 03/19/2045 | Havana | CUB | Right | Right | 6' 2" | 195 lbs | - |
| Soto, Ramon | C | Bighorn Bison | 18 | 08/03/2044 | Camagüey | CUB | Right | Right | 6' 1" | 215 lbs | - |
| Soto, Ricky | SS | Chicago Eclipse | 20 | 12/08/2042 | Villavicencio | COL | Right | Right | 6' 2" | 185 lbs | - |
| Soto, Sherman | 3B | Eagle Rock Ridge Runners | 17 | 07/30/2045 | Trujillo Alto | PUR | Right | Right | 6' 2" | 190 lbs | - |
| Sotomayor, Angelo | C | Pennsylvania Butterflies | 19 | 07/25/2043 | Havana | CUB | Right | Right | 6' 5" | 205 lbs | - |
| Soucy Jr., George | SP | Maple Marauders | 32 | 11/30/2030 | Portage | USA | Left | Left | 6' 8" | 205 lbs | $1,900,000 |
| Soule, Justin | CL | Eureka Hornets | 22 | 09/06/2040 | Little Flock | USA | Left | Left | 6' 0" | 170 lbs | $600,000 |
| Sousal, Rivelino | SP | Montreal Mounties | 17 | 05/21/2045 | Turmero | VEN | Right | Right | 6' 4" | 185 lbs | - |
| Southwick, Randy | 1B | Free Agent | 18 | 03/18/2044 | Columbia | USA | Left | Right | 6' 4" | 200 lbs | - |
| Souza, Izzy | 2B | Hawaii Honu | 17 | 11/15/2045 | Pinar del Rio | CUB | Right | Right | 6' 2" | 185 lbs | - |
| Spargo, Nathan | SP | Kansas City Tornadoes | 18 | 11/18/2044 | Geelong | AUS | Left | Left | 6' 2" | 180 lbs | - |
| Spinola, Felix | 3B | Havana Stogies | 18 | 10/22/2044 | Los Dos Caminos | VEN | Switch | Right | 6' 1" | 180 lbs | - |
| Spottswood, Kevin | LF | Maple Marauders | 24 | 07/26/2038 | Brampton | CAN | Left | Left | 6' 0" | 175 lbs | $1,400,000 |
| Spradling, Jon | RP | Houghton Gremlins | 25 | 05/02/2037 | Carlsbad | USA | Right | Right | 6' 0" | 195 lbs | $600,000 |
| Springer, Eric | LF | Free Agent | 26 | 07/23/2036 | Gilmore | USA | Left | Left | 6' 4" | 200 lbs | - |
| Spurlin, Nick | C | Milwaukee Millers | 22 | 08/14/2040 | Oklahoma City | USA | Right | Right | 6' 0" | 190 lbs | $600,000 |
| Squarebriggs, Terry | C | Havana Stogies | 25 | 12/05/2037 | La Prairie | CAN | Right | Right | 5' 10" | 190 lbs | $600,000 |
| Stagg, Ryan | DH | Bloomington Blazers | 23 | 08/29/2039 | Richmond Hill | CAN | Right | Left | 6' 2" | 205 lbs | $600,000 |
| Stahl, David | C | Free Agent | 23 | 05/14/2039 | Livermore | USA | Right | Right | 6' 0" | 200 lbs | - |
| Staley, Ryan | CF | Walnut Creek Warriors | 18 | 12/02/2044 | Honami | JPN | Right | Right | 6' 1" | 165 lbs | - |
| Standish, Harry | RP | Houghton Gremlins | 24 | 02/12/2038 | Brooklyn | USA | Left | Left | 6' 5" | 200 lbs | - |
| Stanford, Bryan | SP | Havana Stogies | 24 | 01/09/2039 | East Bethel | USA | Right | Right | 6' 0" | 190 lbs | $600,000 |
| Stanley, William | SP | Jacksonville Pilots | 17 | 07/04/2045 | Gladstone | AUS | Right | Right | 6' 6" | 195 lbs | - |
| Staples, Devin | LF | Buffalo Bison | 22 | 01/06/2041 | West Lafayette | USA | Left | Left | 6' 1" | 190 lbs | $600,000 |
| Starkey, Cory | 2B | Buffalo Bison | 25 | 12/14/2037 | Bronx | USA | Right | Right | 6' 1" | 195 lbs | $600,000 |
| Starr, Jay | LF | Bighorn Bison | 23 | 06/14/2039 | Corpus Christi | USA | Right | Right | 6' 4" | 205 lbs | $600,000 |
| Steck, Brad | SP | Free Agent | 33 | 07/15/2029 | Seymour | USA | Left | Right | 6' 0" | 200 lbs | - |
| Stegemann, Owen | SP | Houghton Gremlins | 41 | 09/06/2021 | Santa Cruz | USA | Right | Right | 6' 5" | 200 lbs | $21,200,000 |
| Steinbach, Eric | RP | Bighorn Bison | 30 | 12/08/2032 | New York | USA | Right | Left | 6' 3" | 200 lbs | $1,552,500 |
| Stern, Mike | LF | Free Agent | 28 | 08/13/2034 | Maynard | USA | Left | Left | 5' 10" | 180 lbs | - |
| Stewart, Rich | CF | Montreal Jazz | 17 | 06/18/2045 | Seoul | KOR | Left | Left | 5' 9" | 170 lbs | - |
| Stirling, Kyle | C | Milwaukee Millers | 28 | 03/02/2034 | Huntersville | USA | Right | Right | 5' 10" | 195 lbs | $1,556,800 |
| Stith, Andrew | SP | Quebec Armada | 26 | 10/09/2036 | Clovis | USA | Right | Right | 6' 0" | 195 lbs | $2,828,000 |
| Stith, Wes | SP | Bighorn Bison | 19 | 06/21/2043 | Holly Hill | USA | Right | Right | 6' 1" | 185 lbs | $600,000 |
| Stoecklin, John | C | Jacksonville Pilots | 22 | 08/30/2040 | Monterey Park | USA | Right | Right | 5' 10" | 170 lbs | $600,000 |
| Stoker, Tobias | SS | Seattle Sasquatch | 16 | 03/23/2046 | Rotterdam | NED | Right | Right | 6' 3" | 170 lbs | - |
| Stone, Dennis | 1B | Cairo Pharaohs | 23 | 03/19/2039 | Burlington | USA | Left | Left | 6' 2" | 205 lbs | $1,300,000 |
| Stottlemire, Joe | LF | Free Agent | 26 | 10/17/2036 | Chisholm | USA | Right | Right | 6' 2" | 200 lbs | - |
| Stowers, Dan | LF | Mexico City Luchadores | 23 | 10/06/2039 | Manhattan | USA | Right | Right | 6' 3" | 210 lbs | $600,000 |
| Stradtner, David | RF | Free Agent | 30 | 11/07/2032 | Gilmore | USA | Left | Left | 6' 2" | 200 lbs | - |
| Stranaghan, Kade | C | Free Agent | 18 | 03/16/2044 | Canberra | AUS | Right | Right | 6' 2" | 200 lbs | - |
| Strelioff, Graham | LF | Free Agent | 30 | 11/14/2032 | Toronto | CAN | Left | Left | 6' 2" | 205 lbs | - |
| Strief, Eric | RP | Maple Marauders | 23 | 05/12/2039 | The Woodlands | USA | Right | Right | 6' 1" | 195 lbs | $600,000 |
| Stroebel, Hendri | SP | Free Agent | 16 | 03/29/2046 | Groningen | NED | Right | Right | 6' 4" | 185 lbs | - |
| Strong, Hiroshi | 2B | Free Agent | 18 | 08/25/2044 | Togane | JPN | Right | Right | 6' 1" | 190 lbs | - |
| Stuckless, Wade | 1B | Free Agent | 27 | 08/30/2035 | Dunblane | CAN | Left | Right | 6' 0" | 185 lbs | - |
| Sturm, Adam | RP | Quebec Armada | 26 | 04/14/2036 | Augusta | USA | Left | Left | 6' 2" | 195 lbs | $600,000 |
| Styles, Mike | 3B | Eureka Hornets | 18 | 06/26/2044 | Kyoto | JPN | Right | Right | 5' 11" | 175 lbs | - |
| Suarez, Domingo | SP | Asheville Moonshiners | 17 | 10/26/2045 | Santiago | DOM | Right | Right | 6' 3" | 185 lbs | - |
| Suarez, Mario | 2B | Manhattan Slice | 19 | 03/07/2043 | Santiago | DOM | Right | Right | 6' 3" | 190 lbs | - |
| Suarez, Sergio | SP | Havana Stogies | 19 | 10/02/2043 | Holguín | CUB | Right | Right | 6' 4" | 205 lbs | - |
| Suaste, Jose | SP | Mexico City Luchadores | 18 | 02/25/2044 | Camajuaní | CUB | Right | Right | 6' 4" | 185 lbs | - |
| Suazo, Frank | SP | Walnut Creek Warriors | 19 | 10/01/2043 | San Pedro de Macorís | DOM | Right | Right | 6' 6" | 200 lbs | - |
| Suazo, Ricky | SP | Vancouver Pioneers | 24 | 07/10/2038 | Las Marías | PUR | Left | Left | 6' 6" | 205 lbs | $600,000 |
| Suda, Hideki | RF | Montreal Mounties | 18 | 01/19/2045 | Tomakomai | JPN | Switch | Left | 6' 5" | 190 lbs | - |
| Sullivan, Dylan | 2B | Walnut Creek Warriors | 24 | 03/26/2038 | Houston | USA | Right | Right | 6' 0" | 195 lbs | $600,000 |
| Sullivan, Paul | 2B | Cabo San Lucas Toreros | 22 | 05/22/2040 | Los Angeles | USA | Right | Right | 6' 4" | 200 lbs | $600,000 |
| Sumual, Jati | SP | Manhattan Slice | 18 | 08/16/2044 | Tutong | BRU | Right | Right | 6' 3" | 185 lbs | - |
| Sundai, Ichchaam | SP | Maple Marauders | 17 | 10/13/2045 | Oudtshoorn | RSA | Right | Right | 6' 3" | 185 lbs | - |
| Sung, Jung-tae | RP | Free Agent | 17 | 06/23/2045 | Daegu | KOR | Left | Left | 6' 8" | 200 lbs | - |
| Susanti, Lesmana | RP | Manhattan Slice | 27 | 06/26/2035 | Shah Alam | MAS | Switch | Right | 6' 2" | 200 lbs | $600,000 |
| Suzuki, Kintaro | SP | Mexico City Luchadores | 17 | 06/06/2045 | Hiroshima | JPN | Right | Left | 6' 1" | 175 lbs | - |
| Suzuki, Kouhei | 1B | Asheville Moonshiners | 17 | 08/21/2045 | Furano | JPN | Left | Left | 6' 3" | 220 lbs | - |
| Suzuki, Takahiko | 3B | Hawaii Honu | 16 | 08/19/2046 | Kawagoe | JPN | Right | Right | 6' 0" | 185 lbs | - |
| Suzuki, Takashi | RP | Free Agent | 18 | 09/02/2044 | Tajimi | JPN | Right | Right | 6' 4" | 195 lbs | - |
| Swartz, Dan | C | Free Agent | 21 | 11/28/2041 | Delmar | USA | Right | Right | 6' 3" | 205 lbs | - |
| Sweeney, Chris | SP | Hawaii Honu | 26 | 07/26/2036 | Shreveport | USA | Right | Right | 6' 0" | 180 lbs | $20,000,000 |
| Swindoll, Rich | C | Eureka Hornets | 24 | 04/07/2038 | Escondido | USA | Right | Right | 6' 1" | 200 lbs | $600,000 |
| Swopes, Josh | RP | Buffalo Bison | 24 | 12/09/2038 | Davis | USA | Left | Left | 6' 4" | 210 lbs | $1,100,000 |
