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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | José Leal | 1.449 | 2013 | |
| 2 | Jeremy Fisher | 1.481 | 2013 | |
| 3 | Pedro Rosário | 1.700 | 2016 | |
| 4 | Pablo Cuevas | 1.776 | 2014 | |
| 5 | Pedro Díaz | 1.827 | 2017 | |
| 6 | Quinn O'Neil# | 1.912 | 2054 | |
| 7 | Ted Mills | 1.960 | 2012 | |
| 8 | Héctor González | 1.985 | 2029 | |
| 9 | Jeremy Fisher | 2.016 | 2012 | |
| 10 | Neal Mastro# | 2.031 | 2052 | |
| 11 | Kirk Snyder | 2.046 | 2013 | |
| 12 | Hideki Ohayashi | 2.160 | 2016 | |
| 13 | Diogo Negreiros | 2.181 | 2014 | |
| 14 | Nick Clark# | 2.185 | 2055 | |
| 15 | Guillermo Herrera | 2.265 | 2013 | |
| 16 | John Baniak# | 2.282 | 2048 | |
| 17 | Mike Carter | 2.297 | 2013 | |
| 18 | Ignacio Gil# | 2.310 | 2044 | |
| 19 | Garth Daniels | 2.339 | 2025 | |
| 20 | Anthony Atkinson* | 2.394 | 2012 | |
| 21 | Tadaaki Tahara | 2.396 | 2013 | |
| 22 | Elmer Turner | 2.405 | 2026 | |
| 23 | Brent Welch | 2.447 | 2013 | |
| 24 | Dave Velasco | 2.450 | 2038 | |
| 25 | Ryan Jenkins | 2.471 | 2017 | |
| 26 | Joe McLernon | 2.480 | 2014 | |
| 27 | Ed Latos# | 2.488 | 2052 | |
| 28 | Vaughan Ambrose | 2.517 | 2013 | |
| 29 | Ijaz Kharoti | 2.534 | 2025 | |
| 30 | Oscar Mata | 2.538 | 2033 | |
| 31 | Bob Goudie | 2.551 | 2014 | |
| 32 | Jerry Vega# | 2.552 | 2050 | |
| 33 | Pat McConnell | 2.559 | 2026 | |
| 34 | Adam Sullivan | 2.569 | 2037 | |
| 35 | Grant Huffman | 2.577 | 2032 | |
| 36 | Mike Harper | 2.599 | 2016 | |
| 37 | Miguel Ortiz | 2.623 | 2042 | |
| 38 | Gil Ortiz | 2.641 | 2040 | |
| 39 | Esteban Martínez | 2.646 | 2016 | |
| 40 | Greg Woolery# | 2.647 | 2049 | |
| 41 | Kunio Otsuka | 2.650 | 2033 | |
| 42 | Ánibal Altichioro | 2.653 | 2026 | |
| 43 | Adrien Clément* | 2.663 | 2013 | |
| 44 | Ronaldo Teves | 2.664 | 2026 | |
| 45 | Felipe Rodríguez | 2.670 | 2025 | |
| 46 | Leonardo Reynoso | 2.675 | 2012 | |
| 47 | Eisuke Ota | 2.695 | 2025 | |
| 48 | Vadim Pejemsky | 2.696 | 2014 | |
| 48 | Joe McLernon | 2.696 | 2013 | |
| 50 | Sam Young | 2.700 | 2034 | |
| 50 | Douggie Pitchford | 2.700 | 2028 | |
| 52 | Bob Goudie | 2.705 | 2013 | |
| 53 | Mushanokoji Uchida | 2.715 | 2013 | |
| 54 | Lewis Hunter | 2.735 | 2018 | |
| 55 | Daniel Bonnin | 2.773 | 2018 | |
| 56 | Ruben Vaca# | 2.808 | 2047 | |
| 57 | Sandy Carey | 2.810 | 2016 | |
| 58 | Andy Ericson | 2.819 | 2050 | |
| 59 | Jorge Gutierrez | 2.829 | 2042 | |
| 60 | Patrick Charbonnier | 2.832 | 2030 | |
| 61 | Reynaldo Martínez | 2.840 | 2014 | |
| 62 | Franklin Cruz# | 2.845 | 2049 | |
| 63 | Joey McCalvin | 2.847 | 2033 | |
| 64 | Pablo Costa | 2.849 | 2012 | |
| 65 | Matthew Otto# | 2.860 | 2056 | |
| 66 | Kenny Winston | 2.864 | 2016 | |
| 67 | Pat Ruggles# | 2.871 | 2054 | |
| 68 | Danny Torres# | 2.877 | 2057 | |
| 69 | Jeromir Hamrlik# | 2.878 | 2046 | |
| 70 | Joshua Goldberg | 2.898 | 2013 | |
| 71 | Norberto Rocha | 2.903 | 2013 | |
| 72 | Dave Pinkley | 2.907 | 2040 | |
| 73 | Danny Caravantes | 2.914 | 2040 | |
| 73 | Kyle Frazier# | 2.914 | 2051 | |
| 75 | Michael Walsh | 2.916 | 2023 | |
| 76 | Dave Haskell | 2.937 | 2052 | |
| 77 | Ben Sisley# | 2.940 | 2056 | |
| 78 | Andy Salas | 2.949 | 2038 | |
| 79 | Jason Barfield | 2.952 | 2049 | |
| 80 | Michael Walsh | 2.953 | 2024 | |
| 81 | Jaime González | 2.963 | 2015 | |
| 82 | Cristoforo Giugino | 2.964 | 2020 | |
| 83 | Kichibei Endo | 2.969 | 2028 | |
| 84 | Billy Minter | 2.973 | 2048 | |
| 85 | Harvey Ortiz# | 2.978 | 2057 | |
| 86 | Enrique López | 2.979 | 2020 | |
| 87 | Toyotomi Nakano | 2.986 | 2013 | |
| 88 | Pat Short | 2.990 | 2013 | |
| 89 | Douggie Pitchford | 2.994 | 2029 | |
| 90 | Domeneco Sonnino | 3.000 | 2012 | |
| 91 | Teddy Higuera | 3.017 | 2035 | |
| 92 | Pedro Pérez | 3.029 | 2021 | |
| 93 | Jay Retter | 3.038 | 2028 | |
| 93 | Jason Gates | 3.038 | 2013 | |
| 95 | Elvin Carik# | 3.042 | 2050 | |
| 96 | Song Wa | 3.044 | 2020 | |
| 97 | Máximo Cucalón | 3.060 | 2016 | |
| 98 | Juan Vázquez | 3.061 | 2015 | |
| 99 | Josuke Fujihara | 3.063 | 2027 | |
| 100 | Nicolas Rodrigues | 3.089 | 2015 |
